Buy Pagoclone 10 mg Pellets – Premium Research Chemical | euro-labchems.com

Buy Pagoclone 10 mg Pellets (2-(7-chloro-2,3-dihydro-2-methyl-1-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl)acetamide) CAS Number: 133737-32-3 Molecular Formula: C₂₀H₁₈ClN₃O₂ Molecular Weight: 367.83 g/mol Purity: ≥98.5% (HPLC verified) Dosage per pellet: Exactly 10 mg Pagoclone Form: Compressed pharmaceutical-grade pellets (uniform, scored for precision) Quantity options: 10, 20, 50, 100 pellets Shipping: Discreet worldwide, vacuum-sealed, moisture-proof packaging

euro-labchems.com supplies high-purity Pagoclone 10 mg pellets – a non-benzodiazepine anxiolytic and partial agonist at the benzodiazepine site of the GABA-A receptor. Developed in the 1990s by Rhône-Poulenc Rorer (later Sanofi), Pagoclone (RP 59037) was investigated in clinical trials for generalized anxiety disorder and panic disorder due to its selective anxiolytic profile with reduced sedative and amnesic side effects compared to classical 1,4-benzodiazepines.

What is Pagoclone?

Pagoclone is a cyclopyrrolone derivative that binds with high affinity to the benzodiazepine recognition site of GABA-A receptors, preferentially modulating α2/α3 subunits (anxiolytic) while showing lower intrinsic activity at α1 (sedation) and α5 (memory) subunits. The 10 mg pellet is a standard research/reference dose for studies on subtype-selective GABAergic modulation, anxiolytic mechanisms, and behavioral pharmacology of non-sedating anxiolytics.

Key Product Specifications of Pagoclone 10 mg Pellets

• Pellet size: Small, consistent 3–4 mm diameter
• Excipients: Inert binders for stability & accurate dosing
• Stability: Excellent cool/dark/dry storage (2+ years)
• Potency: 10 mg per pellet – standard research dose

Research Effects & Characteristics

Duration: 6–10 hours Onset: 30–90 minutes Peak: 2–5 hours

Preclinical and clinical literature indicate selective anxiolytic effects: robust reduction of anxiety/fear responses, minimal sedation, preserved motor coordination and cognitive function, mild muscle relaxation at higher doses, and anticonvulsant activity. Frequently described as one of the cleanest anxiolytics with very low amnesic, hypnotic, and ataxic liability.

Possible side effects (dose-dependent, research observations): mild sedation at higher doses, transient dizziness, rebound anxiety, tolerance/dependence potential (lower than classical benzodiazepines), rare paradoxical agitation.

Pagoclone 10 mg pellets are sold strictly for scientific research – not for human/veterinary consumption. Verify local regulations. Full CoA available.

Premium Pagoclone pellets for precise GABA-A subtype research from euro-labchems.com – your trusted specialist.